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Recombinant Human GASP-1/WFIKKNRP Protein(His Tag) (PDMH100312)

All Size Price Qty
500μg $ 1440.00
100μg $ 488.00
20μg $ 158.00
1mg $ 2340.00
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For research use only.

Synonyms UNQ, GASP, Wfikkn, GASP1, WFIKKNRP, WFIKKN2, UNQ9235, PRO31996, GASP-1, hGASP-1, WFDC20B
Species Human
Expression Host Mammalian
Sequence Leu35-His576
Accession Q8TEU8
Calculated Molecular Weight 59.5 kDa
Observed Molecular Weight 80 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 90% as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU/mg of the protein as determined by the LAL method
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Background WAP , kazal , immunoglobulin , kunitz and NTR domain-containing protein 2 , also known as Growth and differentiation factor-associated serum protein 1 , WAP , follistatin , immunoglobulin , kunitz and NTR domain-containing-related protein , WFIKKN-related protein , WFIKKN2 and GASP1 , is a secreted protein that belongs to the WFIKKN family. WFIKKN2 contains two BPTI/Kunitz inhibitor domains , one Ig-like C2-type (immunoglobulin-like) domain , one Kazal-like domain , one NTR domain and one WAP domain. WFIKKN2 is primarily expressed in ovary , testis and brain , but not in liver. In fetal tissues , it is primarily expressed in brain , skeletal muscle , thymus and kidney. WFIKKN2 is a protease-inhibitor that contains multiple distinct protease inhibitor domains. It probably has serine protease-and metalloprotease-inhibitor activity. It inhibits the biological activity of mature myostatin , but not activin. WFIKKN2 protein binds mature GDF8/myostatin and myostatin propeptide and inhibits the biological activity of myostatin.
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