Recombinant Human GDF-15 protein (His Tag) (PDEH101053)
                        For research use only.
| Synonyms | GDF-15, GDF15, Growth/differentiation factor 15 | 
| Species | Human | 
| Expression Host | E.coli | 
| Sequence | Gln151-Ile308 | 
| Accession | Q99988 | 
| Calculated Molecular Weight | 17.3 kDa | 
| Observed Molecular Weight | 20 kDa | 
| Tag | C-His | 
| Bio-activity | Not validated for activity | 
| Form | Lyophilized powder | 
| Purity | > 95% as determined by reducing SDS-PAGE. | 
| Endotoxin | < 10 EU/mg of the protein as determined by the LAL method | 
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. | 
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. | 
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. | 
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. | 
| Background | Growth/differentiation factors (GDF-1 to GDF-15) are members of the BMP family of TGF-beta superfamily proteins. They are produced as inactive preproproteins which are then cleaved and assembled into active secreted homodimers. GDF dimers are disulfide-linked with the exception of GDF-3 and-9. GDF proteins are important during embryonic development, particularly in the skeletal, nervous, and muscular systems. | 
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