Recombinant Human HLA-A*0201 HPV16 E7 complex Protein (C-10His) (PKSH034049)
For research use only.
| Synonyms | HLA-A*0201 HPV16 E7 complex |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | YMLDLQPET&Ile21-Met119&Gly25-Ile308 (Ala269Val) |
| Accession | P61769&P01892 |
| Calculated Molecular Weight | 49.1 kDa |
| Observed Molecular Weight | 55-60 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, 0.06% Tween 80, pH7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | The HPV16 E7 protein plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. E7 protein has both transforming and trans-activating activities. It plays also a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha. |
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