Recombinant Human Interleukin-13/IL-13 Protein (His Tag) (PKSH032617)
                        For research use only.
| Synonyms | BHR, IL13, IL-13, P600, ALRH, BHR1, NC30, Interleukin-13 | 
| Species | Human | 
| Expression Host | HEK293 Cells | 
| Sequence | Gly35-Asn146 | 
| Accession | AAH96139 | 
| Calculated Molecular Weight | 13.4 kDa | 
| Observed Molecular Weight | 13-30 kDa | 
| Tag | C-His | 
| Bio-activity | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 1.5-4.5 ng/ml. | 
| Form | Lyophilized powder | 
| Purity | > 95 % as determined by reducing SDS-PAGE. | 
| Endotoxin | < 0.01 EU per μg of the protein as determined by the LAL method. | 
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. | 
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. | 
| Formulation | 
      Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.  | 
  
| Reconstitution | Please refer to the printed manual for detailed information. | 
| Background | Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. | 
Other Clones
{{antibodyDetailsPage.numTotal}} Results
- 
                                    
                                    
                                    {{item.title}}
                                    
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.:{{item.cat}}
{{index}} {{goods_show_value}}
 
Other Formats
{{formatDetailsPage.numTotal}} Results
Biotinylated
- 
                                    
                                    
                                    {{item.title}}
                                    
Citations ({{item.publications_count}}) Manual MSDS
Cat.No.:{{item.cat}}
{{index}} {{goods_show_value}}
 
- 
                                    
                                    
IF:{{item.impact}}
Journal:{{item.journal}} ({{item.year}})
DOI:{{item.doi}}Reactivity:{{item.species}}
Sample Type:{{item.organization}}
 
- 
                                    
Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}}
 
                            
