Recombinant Human Kallikrein 3/PSA Protein(Fc Tag) (PDMH100343)
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For research use only.
| Synonyms | KLK, Kallikrein, Kallikrein-Related Peptidase, KLK2A, KLK3, APS, KLK2A1, PSA, hK3, Gamma-Seminoprotein, Kallikrein-3, Kallikrein-Related Peptidase 3, P-30 Antigen, Prostate-Specific Antigen, Semenogelase, Seminin, antigen, prostate-specific, APS, Gamma seminoprotein, Gamma-seminoprotein, hK3, Kallikrein 3, Kallikrein related peptidase 3, Kallikrein-3, KLK 3, KLK2A1, Klk3, KLK3, P-30 antigen, P30 antigen, Prostate-specific antigen, Psa, Semenogelase, Seminin |
| Species | Human |
| Expression Host | Mammalian |
| Sequence | Met1-Pro261 |
| Accession | P07288 |
| Calculated Molecular Weight | 53.6 kDa |
| Observed Molecular Weight | 60 kDa |
| Tag | C-Fc |
| Bio-activity | Not validated for activity |
| Form | Lyophilized powder |
| Purity | > 90% as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU/mg of the protein as determined by the LAL method |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Background | KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases. KLK3 contains one peptidase S1 domain. KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence sμggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. |
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