Recombinant Human NECAP2 Protein (His Tag) (PKSH032045)

For research use only.
Synonyms | Adaptin ear-binding coat-associated protein 2, NECAP endocytosis associated protein 2, NECAP2 |
Species | Human |
Expression Host | E.coli |
Sequence | Met 1-Phe263 |
Accession | Q9NVZ3 |
Calculated Molecular Weight | 31.5 kDa |
Observed Molecular Weight | 35 kDa |
Tag | N-His & C-His |
Bio-activity | Not validated for activity |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation | Supplied as a 0.2 μm filtered solution of PBS, 2mM EDTA, 1mM DTT, pH 7.4. |
Reconstitution | Not Applicable |
Background | NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3. |
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