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Recombinant Human NRCAM Protein (Fc Tag) (PKSH033581)

All Size Price Qty
50μg $ 198.00
10μg $ 88.00
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For research use only.

Synonyms KIAA0343, Neuronal cell adhesion molecule, Neuronal surface protein Bravo, Ng-CAM-related, Nr-CAM, gCAM-related cell adhesion molecule, gCAM-related cell adhesion molecule , hBravo
Species Human
Expression Host HEK293 Cells
Sequence Gln25-Asn600
Accession AAI15737.1
Calculated Molecular Weight 91.2 kDa
Observed Molecular Weight 117 kDa
Tag C-Fc
Bio-activity Not validated for activity
Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration.
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