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Recombinant Human Parvulin-14/PIN4 Protein (His Tag) (PKSH032859)

All Size Price Qty
50μg $ 489.00
10μg $ 263.00
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For research use only.

Synonyms PIN4, Parvulin-14, Parvulin-17, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, Peptidyl-prolyl cis-trans isomerase Pin4, Peptidyl-prolyl cis/trans isomerase EPVH, Rotamase Pin4
Species Human
Expression Host E.coli
Sequence Met 1-Lys156
Accession Q9Y237-2
Calculated Molecular Weight 18.8 kDa
Observed Molecular Weight 21 kDa
Tag N-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.5.
Reconstitution Not Applicable
Background Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4(PIN4) is a peptidyl-prolyl cis/trans isomerase (PPIase) which interacts with NIMA and is vital for cell cycle regulation. PIN4 has 2 different isoforms: PAR14 and PAR17. Furthermore, PIN4 protein binds to double-stranded DNA under physiological salt conditions. PIN4 is involved as a ribosomal RNA processing factor in ribosome biogenesis. The PAR14 binds to tightly bent AT-rich stretches of double-stranded DNA, but PAR17 binds to double-stranded DNA.
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