Recombinant Human PDILT Protein (His Tag) (PKSH032959)

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All	Size	Price	Qty
	50μg	$ 198.00	- +
	10μg	$ 88.00	- +

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Synonyms	Protein Disulfide-Isomerase-Like Protein of the Testis, PDILT
Species	Human
Expression Host	HEK293 Cells
Sequence	Ser21-Leu584
Accession	Q8N807
Calculated Molecular Weight	65.5 kDa
Observed Molecular Weight	92 kDa
Tag	C-His
Bio-activity	Not validated for activity
Form	Liquid
Purity	> 90 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.0.
Background	Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid signal sequence and a 564 amino acid mature chain. PDILT contains 1 thioredoxin domain lacks the conserved redox-active Cys at position 417 which is replaced by a Ser residue, suggesting that it lacks thioredoxin activity. PDILT is an enzyme in the endoplasmic reticulum in eukaryotes. It is not a disulfide-linked homodimer. The PDILT protein can interacts with ERO1L and CLGN. PDILT probable redox-inactive chaperone involved in spermatogenesis.

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