Recombinant Human PSPH Protein (His Tag) (PKSH032897)

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All	Size	Price	Qty
	50μg	$ 198.00	- +
	10μg	$ 88.00	- +

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Synonyms	L-3-Phosphoserine Phosphatase, O-Phosphoserine Phosphohydrolase, PSP, PSPH, PSPase, Phosphoserine Phosphatase
Species	Human
Expression Host	E.coli
Sequence	Met 1-Glu225
Accession	P78330
Calculated Molecular Weight	26.1 kDa
Observed Molecular Weight	25-30 kDa
Tag	C-His
Bio-activity	Not validated for activity
Form	Liquid
Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 4M Urea, 5mM EDTA, pH 8.0.
Background	Phosphoserine phosphatase (PSP) is an enzyme that belongs to the serB family. PSPH catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates. Deficiency of this protein is thought to be linked to Williams syndrome. A disorder that results in pre- and postnatal growth retardation; moderate psychomotor retardation and facial features suggestive of Williams syndrome.

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