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Recombinant Human SerpinB3/SCCA1 Protein (Human Cells, His Tag) (PKSH033307)

All Size Price Qty
50μg $ 358.00
10μg $ 158.00
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For research use only.

Synonyms HsT1196, Protein T4-A, SCC, SCCA-1, SCCA1, Serpin B3, Squamous cell carcinoma antigen 1, T4-A, clade B (ovalbumin), member 3, serine (or cysteine) proteinase inhibitor, serpin peptidase inhibitor
Species Human
Expression Host HEK293 Cells
Sequence Met 1-Pro390
Accession P29508
Calculated Molecular Weight 46.0 kDa
Observed Molecular Weight 41-50 kDa
Tag C-His
Bio-activity Not validated for activity
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 0.02% Tween 80,4% Mannitol, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
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