Recombinant Human UBE2T Protein (His Tag) (PKSH033331)

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All	Size	Price	Qty
	50μg	$ 128.00	- +
	10μg	$ 58.00	- +

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Synonyms	Cell Proliferation-Inducing Gene 50 Protein, UBE2T, Ubiquitin Carrier Protein T, Ubiquitin-Conjugating Enzyme E2 T, Ubiquitin-Protein Ligase T
Species	Human
Expression Host	E.coli
Sequence	Met 1-Val197
Accession	Q9NPD8
Calculated Molecular Weight	24.7 kDa
Observed Molecular Weight	25-30 kDa
Tag	N-His
Bio-activity	Not validated for activity
Form	Liquid
Purity	> 95 % as determined by reducing SDS-PAGE.
Endotoxin	< 1.0 EU per μg of the protein as determined by the LAL method.
Storage	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Formulation	Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Background	Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro; UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues; but may prefer 'Lys-11'-; 'Lys-27'-; 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and; upon self-inactivation; may negatively regulate the Faconi pathway.

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