Recombinant HXK I Monoclonal Antibody (AN301256L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human kidney |
| Dilution | IHC 1:200-1:1000 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human HXK I protein |
| Abbre | HXK I |
| Synonyms | HXK, HK1, HK, HK1-ta, HK1-tb, HK1-tc, HKD, HKI, HMSNR, HXK1, hexokinase, RP79, BB404130, Brain form hexokinase, dea, DrHXK1, EC 2.7.1.1, Glycolytic enzyme, HEXOKIN, hexokinase I, Hexokinase PI, Hexokinase type I, Hexokinase-1, Hexokinase-A, HK I, HK1 tb, Hk1-s, im:7148527, mHk1-s, tumor isozyme, wu:fc09d08, wu:fc16e02, wu:fc21e02, wu:fq14b11, zgc:55790, zgc:77618, HXK I |
| Swissprot | |
| Cellular Localization | Mitochondrion outer membrane, Peripheral membrane protein, Cytoplasm, cytosol, The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331). |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Cardiovascular, Signal Transduction, Cancer, Metabolism |
| Clone No. | 5H3 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. |
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Unconjugated
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