Recombinant IFNAR1 Monoclonal Antibody (AN300522P)
For research use only.
| Verified Samples |
Verified Samples in WB: K562, C6, 3T3, HeLa in IF: MCF-7 |
| Dilution | WB 1:1000-1:5000, IHC-P 1:100-1:200, ICC/IF 1:100, FC 1:200-1:1000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC-P, ICC/IF, FC |
| Clonality | Monoclonal |
| Immunogen | Recombinant Mouse IFNAR1 Protein |
| Abbre | IFNAR1 |
| Synonyms | Type I interferon receptor, Interferon alpha/beta receptor, IFN-R-1 IFN-alpha/beta receptor, Cytokine receptor class-II member, Cytokine receptor family 2 member, CRF2, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, IFN-R-1 IFN-alpha/beta receptor 1, Interferon alpha/beta receptor 1, Type I interferon receptor 1, Ifar, Ifnar, Ifnar1, Alpha type antiviral protein, alpha-type, Antiviral protein, AVP, Beta type antiviral protein, beta-type, CD118, IFN alpha REC, IFN alpha receptor, IFN alpha/beta Receptor alpha, IFN beta receptor, IFN Interferon-beta receptor, IFN-alpha/beta receptor 1, IFNBR, IFN-R-1, IFRC, INAR1, Infar, Interferon (alpha beta and omega) receptor 1, interferon alpha and beta receptor subunit 1, Interferon alpha/beta receptor alpha chain, Interferon beta receptor 1, interferon receptor 1, Interferon-alpha receptor |
| Swissprot | |
| Calculated MW | 54 kDa |
| Observed MW |
100 kDa
The actual band is not consistent with the expectation.
Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Cellular Localization | Cell membrane,Late endosome, Lysosome |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS |
| Purification Method | Affinity Purification |
| Clone | B452 |
| Conjugation | Unconjugated |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
| Shipping | Ice bag |
| background | This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008] |
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