Recombinant IGF1R/CD221 Monoclonal Antibody (AN300050P)

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	100μL	$ 380.00

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Verified Samples	Verified Samples in IF: MCF7 Verified Samples in FCM: HeLa
Dilution	ICC/IF 1:20-1:100, FCM 1:25-1:100,
Isotype	IgG
Host	Rabbit
Reactivity	Human
Applications	FCM, ICC/IF
Clonality	Rabbit Monoclonal
Immunogen	Recombinant Human IGF1R / CD221 protein
Abbre	IGF1R
Synonyms	JTK, IGF1R, CD221, IGFIR, IGFR, JTK13, CD221 antigen, IGF-1R, IGF-I R, IGF-I receptor, IGF-IR, insulin-like growth factor 1 receptor
Swissprot	P08069
Cellular Localization	Cell membrane
Concentration	1 mg/mL
Buffer	0.2 μm filtered solution in PBS
Purification Method	Protein A
Research Areas	Signal Transduction, Cancer, Developmental Biology, Neuroscience, Cardiovascular, Metabolism
Clone No.	2C6
Conjugation	Unconjugated
Storage	This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping	Ice bag
background	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Unconjugated