Recombinant INSL3 Monoclonal Antibody (AN301891L)

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	100μL	$ 380.00	- +
	50μL	$ 249.00	- +

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Verified Samples	Verified Samples in IHC: Human testis, Human liver(Negative tissue), Human colon(Negative tissue)
Dilution	IHC 1:200-1:1000
Isotype	IgG, κ
Host	Rabbit
Reactivity	Human,
Applications	IHC
Clonality	Monoclonal;Recombinant
Immunogen	Recombinant human INSL3 fragment
Abbre	INSL3
Synonyms	Insulin-like, Insl, Insulin-like 3, Leydig insulin-like peptide, ley-I-L, Relaxin-like factor, RLF, RLNL, INSL3
Swissprot	P51460
Cellular Localization	Secreted
Concentration	1 mg/mL
Buffer	PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification Method	Protein A purified
Research Areas	Signal Transduction
Clone No.	A607
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	Insulin-like 3 (INSL3), a Leydig cell-specific hormone, is essential for testis descent during foetal life and bone metabolism in adults. Insl3-deficient mice exhibit bilateral undescended testes located high in the abdominal cavity. INSL3 is presumed also to conform to a heterodimeric A-B structure of approximately 6 kDa once released from the producing cells. It is possible that both the mature form of INSL3 (6.6 kDa) and the pro-form(s) of INSL3 (12-14 kDa) are secreted from mammalian Leydig cells.

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Unconjugated