Recombinant Integrin αV Monoclonal Antibody (AN301281L)
For research use only.
| Verified Samples | Verified Samples in IHC: Human bladder cancer |
| Dilution | IHC 1:1000-1:4000 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human Integrin αV protein |
| Abbre | Integrin αV |
| Synonyms | MSK, CD51, MSK8, VNRA, VTNR, Integrin alpha V, ITGAV, vitronectin R, integrin &, alpha-V-V, Integrin αV |
| Swissprot | |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Cardiovascular, Microbiology, Signal Transduction, Cancer, Stem Cells, Immunology |
| Clone No. | B1044 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | ITGAV(integrin subunit alpha V) Homo sapiens The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
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