Recombinant Ku80 Monoclonal Antibody (AN301584L)

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	100μL	$ 380.00	- +
	50μL	$ 249.00	- +

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Verified Samples	Verified Samples in IHC: Mouse colon, Mouse stomach
Dilution	IHC 1:200-1:1000
Isotype	IgG, κ
Host	Rabbit
Reactivity	Mouse
Applications	IHC
Clonality	Monoclonal;Recombinant
Immunogen	Recombinant human Ku80 fragment
Abbre	Ku80
Synonyms	KUB, XRCC, G22P, XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, G22P2
Swissprot	P13010
Cellular Localization	Nucleus
Concentration	1 mg/mL
Buffer	PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification Method	Protein A purified
Research Areas	Epigenetics and Nuclear Signaling
Clone No.	A283
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	Ice bag
background	The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

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Unconjugated