Recombinant Laminin beta 1 Monoclonal Antibody (AN301585L)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human placenta Verified Samples in IF: NIH-3T3 Verified Samples in FCM: A431 |
| Dilution | IHC 1:50-1:100, IF 1:500-1:1000, FCM 1:50-1:100 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC, IF, FCM |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human Laminin beta 1 fragment |
| Abbre | Laminin beta 1 |
| Synonyms | LIS, LAMB, laminin subunit beta, LAMB1, CLM, LIS5, laminin subunit beta-1, CLM, laminin subunit beta-1, LIS5 |
| Swissprot | |
| Cellular Localization | Basement membrane |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Cardiovascular, Signal Transduction, Neuroscience |
| Clone No. | A284 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. |
Other Clones
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Other Formats
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Unconjugated
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