Recombinant Mouse CD48 Protein (His Tag) (PKSM040692)
For research use only.
| Synonyms | AI449234, AW610730, BCM1, BLAST-1, BLAST1, Bcm-1, CD48, MEM-102, SLAM Family Member 2, SLAMF2, Sgp-60 |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Met 1-Arg 216 |
| Accession | NP_031675.1 |
| Calculated Molecular Weight | 23.7 kDa |
| Tag | C-His |
| Bio-activity | Measured by its ability to bind human 2B4 and biotinylated recombinant mouse CD2 in functional ELISA. |
| Form | Lyophilized powder |
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation |
Lyophilized from sterile PBS, pH 7.4 Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
| Background | Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses. |
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