Recombinant Mouse EphA3 Protein (aa 569-984, His & GST Tag) (PKSM040288)
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For research use only.
| Synonyms | AW492086, Cek4, ETK1, End3, Hek, Hek4, Mek4, Tyro4 |
| Species | Mouse |
| Expression Host | Baculovirus-Insect Cells |
| Sequence | Gly569-Val984 |
| Accession | EDK98238.1 |
| Calculated Molecular Weight | 74.3 kDa |
| Observed Molecular Weight | 66 kDa |
| Tag | N-His-GST |
| Bio-activity | Kinase activity untested |
| Form | Liquid |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as sterile solution of 20mM Tris, 500mM NaCl, 10% glycerol, pH 8.0 |
| Background | EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development. |
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