Recombinant Mouse IL16 Protein(Trx Tag) (PDEM100125)

For research use only.
Synonyms | HGNC:5980, HsT19289, IL-16, IL16, IL16, Interleukin 16 precursor, Interleukin-16, LCF, Lymphocyte chemoattractant factor, Neuronal interleukin 16, NIL16, prIL 16, PrIL16, Prointerleukin 16 |
Species | Mouse |
Expression Host | E.coli |
Sequence | Ser1205-Ser1322 |
Accession | O54824 |
Calculated Molecular Weight | 33 kDa |
Observed Molecular Weight | 33 kDa |
Tag | N-Trx |
Bio-activity | Not validated for activity |
Purity | > 90% as determined by reducing SDS-PAGE. |
Endotoxin | < 10 EU/mg of the protein as determined by the LAL method |
Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
Reconstitution | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
Background | Interleukin 16, also known as lymphocyte chemoattractant factor (LCF), refers to the C-terminal peptide of Mouse pro-IL-16 or neuronal IL-16, which are nuclear and cytoplasmic PD2 domain containing proteins. The C-termini of these proteins are cleaved by Caspase-3, resulting in the release of secreted IL-16. Mature IL-16 has been shown to bind the cell surface receptor CD4 and function as an immunomodulatory cytokine. The C-terminal peptide of human and Mouse IL-16 share approximately 86% amino acid sequence identity. |
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