Recombinant Mouse Serpin F1/PEDF Protein (PKSM041232)
For research use only.
| Synonyms | Caspin, Pedf, Pigment epithelium-derived factor, Sdf3, Serpin F1, Stromal cell-derived factor 3. |
| Species | Mouse |
| Expression Host | E.coli |
| Sequence | Asp43-Thr417 |
| Accession | P97298 |
| Calculated Molecular Weight | 42.0 kDa |
| Observed Molecular Weight | 40 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.4. |
| Reconstitution | Not Applicable |
| Background | Serpin F1 is secreted Neurotrophic protein and belongs to the serpin family. Serpin F1 Highly expressed in the liver, gastric glandular mucosa and renal tubules. It is also expressed in the brain, heart, lung retina and testes. It induces extensive neuronal differentiation in retinoblastoma cells. It is potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, exhibits no serine protease inhibitory activity. |
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