Recombinant MUC13 Monoclonal Antibody (AN301769L)
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For research use only.
| Verified Samples |
Verified Samples in WB: HT-29 Verified Samples in IF: HepG2 |
| Dilution | WB 1:1000, IHC-P 1:1000-1:5000, ICC/IF 1:50-1:100, FCM 1:1:50-1:100 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC-P, ICC/IF, FC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | A synthetic peptide of human MUC13 |
| Abbre | MUC13 |
| Synonyms | Muc, UNQ, DRCC, DRCC1, RECC, MUC13, UNQ6194, PRO20221, Down-regulated in colon cancer 1 |
| Swissprot | |
| Calculated MW | 55 kDa |
| Cellular Localization | Cell membrane and Secreted |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Signal Transduction, Cancer |
| Clone | C311391 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Mucin 13 (MUC13) is a high-molecular-weight transmembrane glycoprotein that is frequently and aberrantly expressed in a variety of epithelial carcinomas, including gastric, colorectal, and ovarian cancers. On the basis of the high expression of MUC13 in cancer cells as well as recent laboratory findings suggesting a malignant phenotype of MUC13-transfected cell lines, the oncogenic potential of MUC13 has emerged. The various functional domains of MUC13 may confer oncogenic potential to MUC13. MUC13 exhibits the characteristics suitable as an early marker for cancer screening and presents a promising target for antibody-guided targeted therapy. |
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