Recombinant OPA1 Monoclonal Antibody (AN301265L)
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For research use only.
| Verified Samples | Verified Samples in IHC: Rat brain |
| Dilution | IHC 1:1000-1:4000, WB 1:10000-1:50000, IF 1:200-1:1000, ELISA 1:5000-1:20000, |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human OPA1 protein |
| Abbre | OPA1 |
| Synonyms | MGM, OPA, KIAA, MTDPS, OPA1, BERHS, MGM1, MTDPS14, NPG, NTG, largeG, KIAA0567, OPA1 |
| Swissprot | |
| Cellular Localization | Mitochondrion inner membrane, Single-pass membrane protein, Mitochondrion intermembrane space, Mitochondrion membrane, Detected at contact sites between endoplasmic reticulum and mitochondrion membranes. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Neuroscience, Cardiovascular, Metabolism |
| Clone | B1028 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene. |
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