Recombinant PAX8 Monoclonal Antibody (AN301620L)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid, Mouse thyroid, Rat thyroid Verified Samples in IF: SK-OV-3 |
| Dilution | IHC 1:50-1:100, IF 1:50 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, Rat, Mouse |
| Applications | IHC, IF |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human PAX8 fragment |
| Abbre | PAX8 |
| Synonyms | Paired box, Paired box gene, Paired domain gene, paired box homeotic gene, PAX, PAX8, OTTHUMP00000158659, OTTHUMP00000158660, OTTHUMP00000203723, OTTHUMP00000203724, Paired box 8, Paired box gene 8, paired box homeotic gene 8, Paired box protein Pax 8, Paired box protein Pax-8, Paired domain gene 8, PAX 8 |
| Swissprot | |
| Cellular Localization | Nucleus |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Neuroscience, Epigenetics and Nuclear Signaling |
| Clone No. | A323 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | PAX8 is one of nine transcription factors within the PAX gene family. It has been observed to be expressed during embryonic development however expression attenuates after development in all but a few tissues. Research has indicated that over-expression of PAX proteins in general are not an initiating event in tumorgenesis however they may facilitate malignant development. PAX8 is expressed in 80-96% of all High-grade serous carcinomas (HGSC) and is commonly used as a marker for the disease. In addition PAX8 has become a useful biomarker for differentiating between mullerian mucinous and non-mullerian tumors. PAX8 has also been associated with neoplasms in the kidney and thyroid. |
Other Clones
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Other Formats
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Unconjugated
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