Recombinant PPAR-γ Monoclonal Antibody (AN301397L)
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For research use only.
| Verified Samples | Verified Samples in IHC: Mouse placenta |
| Dilution | IHC 1:500-1:1000, WB 1:2000-1:10000, IF 1:200-1:1000, ELISA 1:5000-1:20000, IP 1:50-1:200, |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, IP, ELISA |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human PPAR-γ protein |
| Abbre | PPAR-γ |
| Synonyms | GLM, CIMT, NR1C, Nuclear receptor subfamily 1 group C member, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma, PPAR gamma, PPARG, Nuclear receptor subfamily 1 group C member 3, PPAR-gamma, PPAR-γ, Peroxisome proliferator-activated receptor gamma |
| Swissprot | |
| Cellular Localization | Nucleus. Cytoplasm, Redistributed from the nucleus to the cytosol through a MAP2K1/MEK1-dependent manner. NOCT enhances its nuclear translocation. |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Epigenetics and Nuclear Signaling, Neuroscience, Stem Cells, Cardiovascular, Metabolism |
| Clone No. | B1164 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | PPARG(peroxisome proliferator activated receptor gamma) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. |
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