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100μL $ 380.00
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For research use only.

Verified Samples Verified Samples in IHC: Human colon, Human small intestine
Dilution IHC-P 1:100-1:500,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC-P
Clonality Rabbit Monoclonal
Immunogen Recombinant Human REG4 Protein
Abbre REG4
Synonyms REG,  Regenerating islet-derived protein,  REG4,  GISP,  REG-IV,  RELP,  Gastrointestinal secretory protein,  Regenerating islet-derived protein 4,  Regenerating islet-derived protein IV,  REG-like protein,  regenerating family member 4
Swissprot
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Immunology,  Cancer
Clone No. 7A10
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
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Unconjugated

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