Recombinant SARS-CoV-2 3C-like Proteinase Protein (His Tag) (PKSR030465)
For research use only.
| Synonyms | 3CL Proteinase, M Proteinase |
| Species | SARS-CoV-2 |
| Expression Host | E.coli |
| Sequence | Ser3264-Gln3569 |
| Accession | P0DTC1 |
| Calculated Molecular Weight | 36.1 kDa |
| Observed Molecular Weight | 33 kDa |
| Tag | N-His |
| Bio-activity | Not validated for activity |
| Form | Liquid |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS, 1 mM EDTA, 10% Glycerol, pH 7.4. |
| Background | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
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