Recombinant Thioredoxin Monoclonal Antibody (AN301254L)
For research use only.
| Verified Samples | Verified Samples in IHC: thyroid carcinoma |
| Dilution | IHC 1:500-1:2000 |
| Isotype | IgG,κ |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant Human Thioredoxin protein |
| Abbre | Thioredoxin |
| Synonyms | TXN, TRDX, TRX, TRX1, ADF, ATL-Derived Factor, SASP, Surface-Associated Sulphydryl Protein, Thioredoxin, Thioredoxin 1, TRX 1, TXN protein, TRDX, TRX 1, TRX1, TXN, TXN protein, ATL derived factor, DKFZp686B1993, MGC61975, Surface associated sulphydryl protein, testicular tissue protein Li 199, THIO, thioredoxin delta 3, TXN delta 3, zgc:92903, Thioredoxin |
| Swissprot | |
| Cellular Localization | Nucleus, Cytoplasm, Secreted, Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces translocation of TRX from the cytoplasm to the nucleus (PubMed:11118054). Secreted by a leaderless secretory pathway (PubMed:1332947). |
| Concentration | 0.2 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A |
| Research Areas | Signal Transduction, Metabolism |
| Clone No. | 5H1 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. |
Other Clones
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Unconjugated
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