Recombinant Thyroglobulin Monoclonal Antibody (AN301675L)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human thyroid Verified Samples in FCM: TT |
| Dilution | IHC 1:100-1:1000, FCM 1:50-1:100 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, |
| Applications | IHC, FCM |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human Thyroglobulin fragment |
| Abbre | Thyroglobulin |
| Synonyms | TDH, TG, AITD3, TGN, AITD 3, hTG, TDH3, THYG, Thyroglobulin, AITD 3, AITD3, hTG, TDH3, Tg, TGN, THYG, Thyroglobulin |
| Swissprot | |
| Cellular Localization | Extracellular region or secreted |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Signal Transduction, Cancer |
| Clone No. | A378 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling in the thyroid follicle lumen. Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream. One dimer produces 7 thyroid hormone molecules. |
Other Clones
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Other Formats
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Unconjugated
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