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Recombinant Tie2/CD202b/TEK Monoclonal Antibody (AN300201P)

All Size Price Qty
100μL $ 380.00
20μL $ 150.00
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For research use only.

Verified Samples Verified Samples in IF: HUVEC
Verified Samples in FCM: HUVEC
Dilution ICC/IF 1:20-1:100,  FCM 1:25-1:100,  
Isotype IgG
Host Rabbit
Reactivity Human
Applications FCM,  ICC/IF
Clonality Rabbit Monoclonal
Immunogen Recombinant Human Tie2 / CD202b / TEK protein
Abbre TEK
Synonyms TIE,  TEK,  CD202B,  GLC3E,  TIE-2,  TIE2,  VMCM,  VMCM1,  Tie2 (Tek),  Angiopoietin 1 receptor,  Angiopoietin-1 receptor,  CD202b antigen,  endothelial,  Endothelial tyrosine kinase,  Endothelium specific receptor tyrosine kinase 2,  hTIE 2,  hTIE2,  Hyk,  p140 TEK,  Soluble TIE2 variant 1,  Soluble TIE2 variant 2,  tek tyrosine kinase,  TEK tyrosine kinase endothelial,  TIE 2,  Tunica interna endothelial cell kinase,  Tyrosine kinase with Ig and EGF homology domains 2,  Tyrosine kinase with Ig and EGF homology domains-2,  Tyrosine protein kinase receptor TEK,  Tyrosine protein kinase receptor TIE 2,  Tyrosine-protein kinase receptor TEK,  Tyrosine-protein kinase receptor TIE-2,  Venous malformations multiple cutaneous and mucosal,  VMCM 1
Swissprot
Cellular Localization Cell membrane, Cell junction, Cell junction, focal adhesion Cytoplasm, cytoskeleton Secreted.
Concentration 1 mg/mL
Buffer 0.2 μm filtered solution in PBS
Purification Method Protein A
Research Areas Signal Transduction,  Cancer,  Cardiovascular,  Stem Cells,  Developmental Biology
Clone No. 8C3
Conjugation Unconjugated
Storage This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Shipping Ice bag
background This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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Unconjugated

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