Recombinant VPAC2 Monoclonal Antibody (AN301688L)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Mouse spleen, Rat spleen Verified Samples in IF: Jurkat |
| Dilution | IHC 1:200-1:500, IF 1:50 |
| Isotype | IgG, κ |
| Host | Rabbit |
| Reactivity | Human, Rat, Mouse |
| Applications | IHC, IF |
| Clonality | Monoclonal;Recombinant |
| Immunogen | Recombinant human VPAC2 fragment |
| Abbre | VPAC2 |
| Synonyms | VIPR, VIP2R, VIPR2 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 1 mg/mL |
| Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant. |
| Purification Method | Protein A purified |
| Research Areas | Neuroscience, Tags and Cell Markers, Signal Transduction, Cancer, Cardiovascular |
| Clone No. | A391 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | Ice bag |
| background | Human VIPR2 (Vasoactive Intestinal Polypeptide Receptor 2), also known as VPAC2, is a 60-70 kDa seven transmembrane glycoprotein receptor, which belongs to the G protein-coupled receptor 2 family of proteins. In its first extracellular region hormone receptor domain (aa 49-114) contains a mature chain, which has three N-linked glycosylation sites and a "Cilia targeting signal", which is composed of and Arg -Composition of Asp-Tyr-Arg sequence. Human VIPR2 has relatively high homology with mouse and rat VIPR2. VIPR2 is mainly expressed in skeletal muscle, CD4+ T cells, smooth muscle cells, dendritic cells, liver precursor cells, single cells, synthetic cells and selective neurons. VIPR2 couples with CAMP-mediated signal transduction pathways, and binds VIP and pituitary adenase activating polypeptide (PACAP). |
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