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For research use only.

Verified Samples Verified Samples in IHC: Human ovarian cancer
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human REST
Abbre REST
Synonyms NRSF,  Neural Restrictive Silencer Factor,  Neural-restrictive silencer factor,  Neuron Restrictive Silencer Factor,  RE1 silencing transcription factor,  RE1-silencing transcription factor,  REST,  REST protein,  Repressor binding to the X2 box,  X2 box repressor,  XBR,  rest
Swissprot
Cellular Localization Nucleus.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Epigenetics and Nuclear Signaling,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
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Unconjugated

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