REST Polyclonal Antibody (E-AB-17813)

For research use only.
Verified Samples |
Verified Samples in IHC: Human ovarian cancer |
Dilution | IHC 1:30-1:150 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human REST |
Abbre | REST |
Synonyms | NRSF, Neural Restrictive Silencer Factor, Neural-restrictive silencer factor, Neuron Restrictive Silencer Factor, RE1 silencing transcription factor, RE1-silencing transcription factor, REST, REST protein, Repressor binding to the X2 box, X2 box repressor, XBR, rest |
Swissprot | |
Cellular Localization | Nucleus. |
Concentration | 1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Antigen affinity purification |
Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described. |
Other Clones
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Other Formats
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Unconjugated
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