For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human esophagus cancer |
| Dilution | IHC 1:40-1:200 |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RFX6 |
| Abbre | RFX6 |
| Synonyms | 6, DNA binding protein RFX6 , RFX6, RFX6 regulatory factor X, Regulatory factor X domain containing protein 1 |
| Swissprot | |
| Cellular Localization | Nucleus |
| Concentration | 0.84 mg/mL |
| Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Purification Method | Antigen affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis. |
Other Clones
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Other Formats
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