RGS1 Polyclonal Antibody (E-AB-11534)
For research use only.
| Verified Samples |
Verified Samples in WB: RAW264.7 |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human RGS1 |
| Abbre | RGS1 |
| Synonyms | 1R20, B cell activation protein BL34, B-cell activation protein BL34, B-cell specific, BL34, Early response protein 1R20, IER 1, IER1, IR20, Immediate early response 1 B cell specific, Regulator of G protein signalling 1, Regulator of G-p, immediate-early response 1 |
| Swissprot | |
| Calculated MW | 24 kDa |
| Cellular Localization | Cytosol, Plasma Membrane, extrinsic component of cytoplasmic side of Plasma Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. |
Other Clones
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Other Formats
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Unconjugated
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