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For research use only.

Verified Samples Verified Samples in WB: Human brain malignant glioma, Jurkat, Raji, 231, Human fetal brain, Hela
Verified Samples in IHC: Human liver cancer, Human lung cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human RHEB
Abbre RHEB
Synonyms GTP binding protein Rheb,  GTP-binding protein Rheb,  MGC111559,  RHEB,  RHEB 2,  RHEB2,  Ras homolog enriched in brain,  Ras homolog enriched in brain 2,  Rheb,  formerly
Swissprot
Calculated MW 20 kDa
Cellular Localization Cell membrane.
Concentration 1.6 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Metabolism,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Other Clones

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Unconjugated

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