RHOB Polyclonal Antibody (E-AB-12248)
For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain, Mouse fetal brain |
| Dilution | WB 1:1000-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RHOB |
| Abbre | RHOB |
| Synonyms | ARH6, ARHB, Aplysia RAS-related homolog 6, H6, MST081, MSTP081, RHOB, RHOH6, Rho cDNA clone 6, Rho related GTP binding protein RhoB Precursor, Rho-related GTP-binding protein RhoB, Rhob, member B, oncogene RHO H6, ras homolog family member B, ras homolog gene family |
| Swissprot | |
| Calculated MW | 22 kDa |
| Cellular Localization | Late endosome membrane. Cell membrane. Nucleus. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Ras homolog gene family, member B, also known as RHOB, is a protein which in humans is encoded by the RHOB gene.RHOB is a member of the Rho GTP-binding protein family.Mediates apoptosis in neoplastically transformed cells after DNA damage. It is not necessary for development but affects cell adhesion and growth factor signaling in transformed cells. It plays a negative role in tumorigenesis as deletion causes tumor formation. It involved in intracellular protein trafficking of a number of proteins, and serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Required for genotoxic stress-induced cell death in breast cancer cells. |
Other Clones
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Other Formats
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Unconjugated
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