RITA1 Polyclonal Antibody (E-AB-19212)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RITA1 |
| Abbre | RITA1 |
| Synonyms | C12orf52, Chromosome 12 open reading frame 52, RBPJ interacting and tubulin associated 1, RBPJ interacting and tubulin associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus. Cytoplasm>cytoskeleton>centrosome. Shuttles rapidly between the cytoplasm and the nucleus. The function of centrosome localization is still unclear. |
| Concentration | 1.02 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Developmental biology, Neuroscience, Signal transduction, Stem cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis. |
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