ROR1 Polyclonal Antibody (E-AB-13684)
For research use only.
Verified Samples |
Verified Samples in IHC: Human lung cancer, Human prostate cancer, Human heart |
Dilution | IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human ROR1 |
Abbre | ROR1 |
Synonyms | Inactive tyrosine protein kinase transmembrane receptor ROR1, MGC99659, NTRKR1, Neurotrophic tyrosine kinase, Neurotrophic tyrosine kinase receptor related 1, OTTHUMP00000010573, OTTHUMP00000010574, OTTM, dJ537F10.1, receptor related 1 |
Swissprot | |
Cellular Localization | Membrane. |
Concentration | 0.9 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cancer, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Other Clones
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Other Formats
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Unconjugated
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