RRAGA Polyclonal Antibody (E-AB-15366)
For research use only.
| Verified Samples |
Verified Samples in WB: HepG2, Hela |
| Dilution | WB 1:500-1:2000 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human RRAGA |
| Abbre | RRAGA |
| Synonyms | Adenovirus E3 14.7 kDa-interacting protein 1, FIP-1, RRAGA, Rag A, RagA, Ras-related GTP-binding protein A |
| Swissprot | |
| Calculated MW | 37 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14.7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Microbiology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Ras-related GTP-binding protein A is a protein that in humans is encoded by the RRAGAgene.Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB.This is a crucial step in the activation of the TOR signaling cascade by amino acids.Involved in the RCC1/Ran-GTPase pathway.May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. |
Other Clones
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Other Formats
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Unconjugated
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