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For research use only.

Verified Samples Verified Samples in WB: RAW264.7
Verified Samples in IHC: Human lung cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human RTN4
Abbre RTN4
Synonyms NSP,  Nogo,  Nogo A,  Nogo B,  RTN x,  RTN4,  RTN4A,  RTNX,  Reticulon 4,  Reticulon 5
Swissprot
Calculated MW 40 kDa
Cellular Localization Endoplasmic reticulum, endoplasmic reticulum membrane, multi-pass membrane protein, Note=Anchored to the membrane of the endoplasmic reticulum through 2 putative transmembrane domains.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Neuroscience
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Other Clones

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Unconjugated

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