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For research use only.

Verified Samples Verified Samples in IHC: Rat brain
Dilution IHC 1:2000-1:4700
Isotype IgG
Host Rabbit
Reactivity Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant Human S100B protein expressed by E.coli
Abbre S100B
Synonyms NEF,  Protein S100 B,  Protein S100-B,  S 100 calcium binding protein beta chain,  S 100 protein beta chain,  S-100 protein beta chain,  S-100 protein subunit beta,  S100,  S100 calcium binding protein beta (neural),  S100 calcium-binding protein B,  S100 protein beta chain
Swissprot
Concentration 1 mg/mL
Buffer PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method Antigen Affinity Purification
Research Areas Cancer,  Cell Biology,  Epigenetics and Nuclear Signaling,  Stem cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs and has been implicated in the regulation of cellular activities such as metabolism, motility and proliferation. In the nervous system, S100B is constitutively released by astrocytes into the extracellular space and at nanomolar concentrations, it can promote neurite outgrowth and protect neurons against oxidative stress. Within the central nervous system (CNS), S100B is thought to be a marker for astroglial activation, linking astrocyte dysfunction to schizophrenia. In addition to astrocytes, S100B is released from many cell types, such as, adipocytes, chondrocytes, cardiomyocytes and lymphocytes. Serum S100B represents a new bomarker for mood disorders.
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Unconjugated

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