SCN11A Polyclonal Antibody (E-AB-12863)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human breast cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SCN11A |
| Synonyms | NAV1.9, NaN, PN 5, PN5, Peripheral nerve sodium channel 5, SCN 11A, SCN 12A, SCN12A, SCNBA, SNS 2, SNS2, Scn11a, Sensory neuron sodium channel 2, Sodium channel protein type 11 subunit alpha, Sodium channel protein type XI subunit alpha, Sodium channel voltage gate, hNaN |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers. |
Other Clones
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Other Formats
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Unconjugated
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