For research use only.
| Verified Samples | Verified Samples in IHC: Human liver, Human kidney |
| Dilution | IHC 1:75-1:150 |
| Clonality | Polyclonal |
| Immunogen | Recombinant Human SDHB protein expressed by E.coli |
| Abbre | SDHB |
| Synonyms | Ip, DHSB, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, PGL 4, PGL4, SDH, SDH 1, SDH1, SDH2, SDHIP, SdhB, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitocho, homolog of, mitochondrial, CWS2 |
| Swissprot | |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
Other Clones
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Other Formats
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Unconjugated
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