SDHB Polyclonal Antibody (D-AB-10362L)
 
                        For research use only.
| Verified Samples | Verified Samples in IHC: Human liver, Human kidney | 
| Dilution | IHC 1:75-1:150 | 
| Isotype | IgG | 
| Host | Rabbit | 
| Reactivity | Human | 
| Applications | IHC | 
| Clonality | Polyclonal | 
| Immunogen | Recombinant Human SDHB protein expressed by E.coli | 
| Abbre | SDHB | 
| Synonyms | Ip, DHSB, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, PGL 4, PGL4, SDH, SDH 1, SDH1, SDH2, SDHIP, SdhB, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitocho, homolog of, mitochondrial, CWS2 | 
| Swissprot | |
| Concentration | 1 mg/mL | 
| Buffer | PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4 | 
| Purification Method | Antigen Affinity Purification | 
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction | 
| Conjugation | Unconjugated | 
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. | 
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. | 
| background | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. | 
Other Clones
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Other Formats
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Unconjugated
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