SDHB Polyclonal Antibody (E-AB-16795)
For research use only.
| Verified Samples |
Verified Samples in WB: PC-3, HepG2, Human fetal liver Verified Samples in IHC: Human thyroid cancer, Human liver cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SDHB |
| Abbre | SDHB |
| Synonyms | CWS2, DHSB, FLJ92337, Ip, Iron sulfur subunit, Iron sulfur subunit of complex II, Iron-sulfur subunit of complex II, PGL 4, PGL4, SDH, SDH 1, SDH1, SDH2, SDHIP, SdhB, Su, Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial, homolog of, mitochondrial |
| Swissprot | |
| Calculated MW | 32 kDa |
| Cellular Localization | Mitochondrion inner membrane. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell biology, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. |
Other Clones
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Other Formats
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Unconjugated
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