For research use only.
| Verified Samples |
Verified Samples in IF: C6, U-2OS |
| Dilution | IF 1:50-1:200 |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human SETD2 (NP_054878.5). |
| Synonyms | HBP231, HIF-1, HIP-1, HSPC069, HYPB, KMT3A, LLS, SET2, SETD2, p231HBP |
| Swissprot | |
| Cellular Localization | Nucleus. Chromosome. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Other Clones
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