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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human lung cancer
Dilution IHC 1:100-1:300
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human SFRP1
Abbre SFRP1
Synonyms FRP,  FRP 1,  FRP-1,  FRP1,  Frizzled related protein 1,  FrzA,  SARP 2,  SARP-2,  SARP2,  SF,  Secreted apoptosis related protein 2,  Secreted apoptosis-related protein 2,  Secreted frizzled related protein,  Secreted frizzled related protein 1,  Secreted frizzled-related protein 1
Swissprot
Cellular Localization Secreted. Cell membrane or extracellular matrix-associated. Released by heparin-binding.
Concentration 0.4 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Developmental Biology,  Neuroscience,  Stem Cells
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
Other Clones

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Unconjugated

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