SFRP1 Polyclonal Antibody (E-AB-16059)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human lung cancer |
| Dilution | IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SFRP1 |
| Abbre | SFRP1 |
| Synonyms | FRP, FRP 1, FRP-1, FRP1, Frizzled related protein 1, FrzA, SARP 2, SARP-2, SARP2, SF, Secreted apoptosis related protein 2, Secreted apoptosis-related protein 2, Secreted frizzled related protein, Secreted frizzled related protein 1, Secreted frizzled-related protein 1 |
| Swissprot | |
| Cellular Localization | Secreted. Cell membrane or extracellular matrix-associated. Released by heparin-binding. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Developmental Biology, Neuroscience, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. |
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