SH3KBP1 Polyclonal Antibody (E-AB-11578)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human liver cancer, Human breast cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SH3KBP1 |
| Abbre | SH3KBP1 |
| Synonyms | CD2 binding protein 3, CD2-binding protein 3, CD2BP3, CIN 85, CIN85, Cbl interacting protein, Cbl interacting protein of 85 kDa, Cbl-interacting protein of 85 kDa, GIG 10, GIG10, H, HSB 1, HSB-1, HSB1, Human Src family kinase binding protein 1, c Cbl interacting protein |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton. Cytoplasmic vesicle membrane. Cell junction>synapse>synaptosome. Cell junction>focal adhesion. Localized in endocytic vesicles containing clustered receptors. Colocalizes with ASAP1 in vesicular structures. Colocalized with actin microfilaments and focal adhesions (By similarity). Colocalized with MAGI2 in synaptosomes. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants. |
Other Clones
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Other Formats
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Unconjugated
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