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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human breast cancer
Dilution IHC 1:30-1:150
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human SH3KBP1
Synonyms CD2 binding protein 3,  CD2-binding protein 3,  CD2BP3,  CIN 85,  CIN85,  Cbl interacting protein,  Cbl interacting protein of 85 kDa,  Cbl-interacting protein of 85 kDa,  GIG 10,  GIG10,  H,  HSB 1,  HSB-1,  HSB1,  Human Src family kinase binding protein 1,  c Cbl interacting protein
Swissprot
Cellular Localization Cytoplasm>cytoskeleton. Cytoplasmic vesicle membrane. Cell junction>synapse>synaptosome. Cell junction>focal adhesion. Localized in endocytic vesicles containing clustered receptors. Colocalizes with ASAP1 in vesicular structures. Colocalized with actin microfilaments and focal adhesions (By similarity). Colocalized with MAGI2 in synaptosomes.
Concentration 0.6 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Other Clones

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Unconjugated

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