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For research use only.

Verified Samples Verified Samples in IHC: Human thyroid cancer, Human brain
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human SIGLEC5
Abbre SIGLEC5
Synonyms CD170,  CD170 antigen,  CD33 antigen-like 2,  CD33L2,  OB-BP2,  OB-binding protein 2,  OBBP2,  Obesity-binding protein 2,  Sialic acid binding Ig-like lectin 5,  Sialic acid binding immunoglobulin-like lectin 5,  Sialic acid-bin,  Sialic acid-binding Ig-like lectin 5,  mSiglec-F
Swissprot
Cellular Localization Membrane.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Immunology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.
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Unconjugated

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