SIGLEC5 Polyclonal Antibody (E-AB-11046)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human thyroid cancer, Human brain |
| Dilution | IHC 1:25-1:100 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SIGLEC5 |
| Abbre | SIGLEC5 |
| Synonyms | CD170, CD170 antigen, CD33 antigen-like 2, CD33L2, OB-BP2, OB-binding protein 2, OBBP2, Obesity-binding protein 2, Sialic acid binding Ig-like lectin 5, Sialic acid binding immunoglobulin-like lectin 5, Sialic acid-bin, Sialic acid-binding Ig-like lectin 5, mSiglec-F |
| Swissprot | |
| Cellular Localization | Membrane. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
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